Source:http://linkedlifedata.com/resource/umls/id/C0033627
MSH: Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.,CSP: process of unfolding or otherwise grossly changing the tertiary structure of a protein; usually applies to experimental treatments, although may occur in biological contexts (e.g., "heat shock").,GO: Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds. [GOC:kd, ISBN:3110145359]