Prochlorperazine

Source:http://linkedlifedata.com/resource/umls/id/C0033229

MSH: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612),CSP: phenothiazine derivative used chiefly as an antiemetic.,NCI: A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics.,PDQ: A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&cod

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