Procarbazine

Source:http://linkedlifedata.com/resource/umls/id/C0033223

MSH: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.,CSP: antineoplastic agent specific for the S phase of the cell cycle, used in combination with mechlorethamine, vincristine, and prednisone (MOPP protocol) in the treatment of Hodgkin's disease, and in treatment of other neoplasms.,NCI: The active ingredient in a drug that is used to treat advanced Hodgkin lymphoma and is being studied in the treatment of other types of cancer. Procarbazine blocks cells from making proteins and damages DNA. It may kill cancer cells. It is a type of antineoplastic agent and a type of alkylating agent.,NCI: A methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarbazine, after metabolic activation, appears to inhibit the trans-methylation of methionine into transfer RNA (t-RNA), thereby preventing protein synthesis and conseq

Download in:

View as