podophyllin

Source:http://linkedlifedata.com/resource/umls/id/C0032333

MSH: Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses.,CSP: caustic extract from the roots of Podophyllum species; it contains podophyllotoxin and its congeners and is very irritating to mucous membranes and skin; it is a violent purgative that may cause CNS damage and teratogenesis; used as a paint for warts, skin neoplasms, and senile keratoses.,NCI: A resin extracted from the root of the plant Podophyllum sp. Berberidaceae (mandrake), which contains numerous compounds, among which podophyllotoxin is the principal active component. Podophyllin arrests mitosis in metaphase. Podophyllotoxin offers advantages over podophyllin in terms of purity, stability and lack of systemic toxicity. (NCI04)

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