umls-concept:C0030576 | skos:definition | MSH: An oligosaccharide antibiotic produced by various STREPTOMYCES.,NCI: An aminoglycoside antibiotic derived from Streptomyces rimosus var. paromomycinus, with amebicidal and antibacterial activity. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation, thereby leading to inhibition of protein synthesis followed by cell death. | lld:umls |