Norepinephrine Bitartrate

Source:http://linkedlifedata.com/resource/umls/id/C0028333

NCI: A bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine bitartrate acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action.,NCI: The bitartrate salt form of levarterenol, the levorotatory isomer of norepinephrine with a vasoconstrictor effect. Levarterenol binds to alpha and beta-1 receptor sites of sympathetic effector cells, thereby causing vasoconstriction of the radial smooth muscle of the arteries, arterioles, and veins and increasing myocardial contractility, heart rate, automaticity, and artrioventricular (AV) conduction, respectively. Stimulation of the beta-2 adrenergic receptors causes bronchiolar and vascular smooth musc

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