Source:http://linkedlifedata.com/resource/umls/id/C0028096
MSH: Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.,CHV: a kind of cancer treatment drug,CHV: a kind of cancer treatment drug,NCI: A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called nitrosoureas.,PDQ: A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38853&idtype=1" active clinical trials or "http://www.cancer.gov/Search/Clinica