| umls-concept:C0027793 | skos:definition | MSH: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.,CSP: communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.,GO: The neurological system process in which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation. [GOC:curators, ISBN:0815316194],GO: The process of communication from a neuron to a target (neuron, muscle, or secretory cel | lld:umls |
