Myosin Light Chain Kinase

Source:http://linkedlifedata.com/resource/umls/id/C0027120

MSH: An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.,CSP: mediates calcium-calmodulin dependent phosphorylation of myosin light chain (20 kD) subunits to initiate smooth muscle and other actomyosin based cellular contractility systems inactivated by cyclic AMP dependent protein kinase, accounting for relaxant effect of cAMP.,NCI: Myosin Light Polypeptide Kinase, encoded by the MYLK gene, is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in

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