Mitolactol

Source:http://linkedlifedata.com/resource/umls/id/C0026252

MSH: Alkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs.,NCI: An anticancer drug that belongs to the family of drugs called alkylating agents.,PDQ: A synthetic derivative of hexitol with antineoplastic and radiosensitizing properties. Mitolactol alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA and RNA synthesis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39216&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39216&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C662" NCI Thesaurus),NCI: A synthetic derivative of hexitol with antineoplastic and radiosensitizing properties. Mitolactol alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA and RNA synthesis. (NCI04)

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