umls-concept:C0019796 | skos:definition | NCI: High mobility group protein B1 (215 aa, ~25 kDa) is encoded by the human HMGB1 gene. This protein is involved in the regulation of both chromatin structure and DNA topology.,MSH: A 24-kDa HMGB protein that binds to and distorts the minor grove of DNA. | lld:umls |