Source:http://linkedlifedata.com/resource/umls/id/C0016860
MSH: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.,CSP: sulfamyl saluretic and diuretic; has a fast onset and short duration of action and is used in edema and chronic renal insufficiency.,CHV: a drug used as a diuretic,CHV: a drug used as a diuretic,CHV: a drug used as a diuretic,PDQ: An anthranilic derivative and loop diuretic with antihypertensive effect. Furosemide blocks the Na-K-Cl cotransporter (NKCC) in the luminal membrane of the thick ascending limb of the loop of Henle in the kidney, by binding to the Cl-binding site located in the cotransporter's transmembrane domain, thereby inhibiting reabsorption of sodium, chloride, potassium ions and water. This agent reduces plasma and extracellular fluid volume resulting in decreased blood pressure and cardiac output. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39247&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrial