| umls-concept:C0016368 | skos:definition | MSH: A phenothiazine used in the treatment of PSYCHOSES. Its properties and uses are generally similar to those of CHLORPROMAZINE.,CSP: 2-trifluoromethyl derivative of perphenazine, used in treatment of psychoses.,NCI: A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia.,NCI: A drug that is used to treat mental and emotional disorders and is being studied in the treatment of multiple myeloma. Fluphenazine may stop tumor growth by keeping myeloma cells from dividing and causing them to die. It is a type of antipsychotic. | lld:umls |
