Clomiphene

Source:http://linkedlifedata.com/resource/umls/id/C0009008

MSH: A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.,CSP: USP lists as a gonad stimulating principle; is a fertility inhibitor in male and female rats, but is a fertility stimulant in women used to induce multiple births.,NCI: A triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04)

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