Source:http://linkedlifedata.com/resource/umls/id/C0008864
CSP: amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver; chemical name L-ornithine, N5-(aminocarbonyl).,PDQ: A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product . Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464795&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464795&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C53406" NCI Thesaurus),NCI: A non