| umls-concept:C0006057 | skos:definition | MSH: A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208),CSP: disease caused by potent protein neurotoxins produced by Clostridium botulinum, which interfere with the presynaptic release of acetylcholine at the neuromuscular junction; clinical features include abdominal pain, vomiting, acute paralysis, blurred vision and diplopia; botulism may be classified into several subtypes such as food borne, infant, wound, and others.,MEDLINEPLUS: <p>Botulism is a rare but serious illness caused by a bacterium called <em>Clostridium botulinum</em>, which occurs in soil. It produces a toxin that affects your nerves. | lld:umls |
