Seirogan is a beechwood extract composed of guaiacol, creosol and other related phenolic compounds which is widely used as an anti-diarrhoeal agent in Asia. Abnormalities in water and electrolyte transport are often the cause of diarrhoea, but the mechanism of action of seirogan on small intestinal and colonic mucosal ion transport is unknown.
Oklahoma Foundation for Digestive Research, Basic Sciences Laboratory, VA Medical Center, University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA. Beverley-Greenwood@ouhsc.edu
