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pubmed-article:9871661pubmed:abstractTextA series of hydrolytically-stable aza analogs of arabinofuranose was prepared and evaluated against Mycobacterium tuberculosis and M. avium. The compounds were designed to mimic the putative arabinose donor involved in biogenesis of the essential cell wall polysaccharide, arabinogalactan. Though most compounds displayed little activity in cell culture, one compound showed significant activity in infected macrophage models.lld:pubmed
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pubmed-article:9871661pubmed:articleTitleHomologated aza analogs of arabinose as antimycobacterial agents.lld:pubmed
pubmed-article:9871661pubmed:affiliationDepartment of Organic Chemistry, Southern Research Institute, Birmingham, AL 35255, USA.lld:pubmed
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