pubmed-article:9828124 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9828124 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:9828124 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
pubmed-article:9828124 | lifeskim:mentions | umls-concept:C1334043 | lld:lifeskim |
pubmed-article:9828124 | lifeskim:mentions | umls-concept:C1517488 | lld:lifeskim |
pubmed-article:9828124 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:9828124 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:9828124 | pubmed:dateCreated | 1999-1-21 | lld:pubmed |
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pubmed-article:9828124 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9828124 | pubmed:abstractText | The pathway controlling sex determination in the nematode Caenorhabditis elegans is a model for the genetic control of cell-fate determination. We report here the cloning and characterization of a new mouse gene family with homology to FEM-1, a signal-transducing regulator in the C. elegans sex-determination pathway. This gene family consists of two known members, designated Fem1a and Fem1b. The highest degree of homology between the two mouse proteins and the nematode protein is in a domain that encodes seven sequential ANK repeats. The Fem1a gene localizes to chromosome 17 and is highly expressed in adult heart and skeletal muscle. The Fem1b gene localizes to chromosome 9 and is highly expressed in adult testis. Both genes are expressed during embryogenesis. The existence of FEM-1 homologs in the mouse raises the possibility that evolutionary conservation of ancient FEM-1 signaling interactions may play a role in vertebrate cell-fate determination. | lld:pubmed |
pubmed-article:9828124 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9828124 | pubmed:language | eng | lld:pubmed |
pubmed-article:9828124 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9828124 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:9828124 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9828124 | pubmed:month | Dec | lld:pubmed |
pubmed-article:9828124 | pubmed:issn | 0888-7543 | lld:pubmed |
pubmed-article:9828124 | pubmed:author | pubmed-author:MaherJ FJF | lld:pubmed |
pubmed-article:9828124 | pubmed:author | pubmed-author:SeldinM FMF | lld:pubmed |
pubmed-article:9828124 | pubmed:author | pubmed-author:LUCC | lld:pubmed |
pubmed-article:9828124 | pubmed:author | pubmed-author:Ventura-Holma... | lld:pubmed |
pubmed-article:9828124 | pubmed:copyrightInfo | Copyright 1998 Academic Press. | lld:pubmed |
pubmed-article:9828124 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9828124 | pubmed:day | 1 | lld:pubmed |
pubmed-article:9828124 | pubmed:volume | 54 | lld:pubmed |
pubmed-article:9828124 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9828124 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9828124 | pubmed:pagination | 221-30 | lld:pubmed |
pubmed-article:9828124 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:9828124 | pubmed:meshHeading | pubmed-meshheading:9828124-... | lld:pubmed |
pubmed-article:9828124 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9828124 | pubmed:articleTitle | The murine fem1 gene family: homologs of the Caenorhabditis elegans sex-determination protein FEM-1. | lld:pubmed |
pubmed-article:9828124 | pubmed:affiliation | Department of Medicine, Division of Hematology, University of Mississippi Medical Center, Jackson, Mississippi, 39216, USA. | lld:pubmed |
pubmed-article:9828124 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9828124 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:9828124 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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