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pubmed-article:9820935pubmed:abstractTextMost dry-eye symptoms result from an abnormal, nonlubricative ocular surface that increases shear forces under the eyelids and diminishes the ability of the ocular surface to respond to environmental challenges. This ocular-surface dysfunction may result from immunocompromise due to systemic autoimmune disease or may occur locally from a decrease in systemic androgen support to the lacrimal gland as seen in aging, most frequently in the menopausal female.lld:pubmed
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pubmed-article:9820935pubmed:articleTitleThe pathology of dry eye: the interaction between the ocular surface and lacrimal glands.lld:pubmed
pubmed-article:9820935pubmed:affiliationDepartment of Biological Sciences, Allergan, Inc., Irvine, CA 92713-9534, USA. stern_michael@allergan.comlld:pubmed
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