Linked Life Data

9733861

Source:http://linkedlifedata.com/resource/pubmed/id/9733861

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:9733861rdf:typepubmed:Citationlld:pubmed
pubmed-article:9733861lifeskim:mentionsumls-concept:C0205725lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C1622204lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C0017968lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C1179435lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C0017337lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C0439855lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C1705248lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C2700640lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C1548799lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C1524073lld:lifeskim
pubmed-article:9733861lifeskim:mentionsumls-concept:C0449432lld:lifeskim
pubmed-article:9733861pubmed:issue10lld:pubmed
pubmed-article:9733861pubmed:dateCreated1998-10-7lld:pubmed
pubmed-article:9733861pubmed:abstractTextThe human cytomegalovirus (HCMV) gCIII envelope complex is composed of glycoprotein H (gH; gpUL75), glycoprotein L (gL; gpUL115), and a third, 125-kDa protein not related to gH or gL (M. T. Huber and T. Compton, J. Virol. 71:5391-5398, 1997; L. Li, J. A. Nelson, and W. J. Britt, J. Virol. 71:3090-3097, 1997). Glycosidase digestion analysis demonstrated that the 125-kDa protein was a glycoprotein containing ca. 60 kDa of N-linked oligosaccharides on a peptide backbone of 65 kDa or less. Based on these biochemical characteristics, two HCMV open reading frames, UL74 and TRL/IRL12, were identified as candidate genes for the 125-kDa glycoprotein. To identify the gene encoding the 125-kDa glycoprotein, we purified the gCIII complex, separated the components by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and subjected gH and the 125-kDa glycoprotein to amino acid microsequence analysis. Microsequencing of an internal peptide derived from purified 125-kDa glycoprotein yielded the amino acid sequence LYVGPTK. A FASTA search revealed an exact match of this sequence to amino acids 188 to 195 of the predicted product of the candidate gene UL74, which we have designated glycoprotein O (gO). Anti-gO antibodies reacted in immunoblots with a protein species migrating at ca. 100 to 125 kDa in lysates of HCMV-infected cells and with 100- and 125-kDa protein species in purified virions. Anti-gO antibodies also immunoprecipitated the gCIII complex and recognized the 125-kDa glycoprotein component of the gCIII complex. Positional homologs of the UL74 gene were found in other betaherpesviruses, and comparisons of the predicted products of the UL74 homolog genes demonstrated a number of conserved biochemical features.lld:pubmed
pubmed-article:9733861pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:languageenglld:pubmed
pubmed-article:9733861pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:citationSubsetIMlld:pubmed
pubmed-article:9733861pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9733861pubmed:statusMEDLINElld:pubmed
pubmed-article:9733861pubmed:monthOctlld:pubmed
pubmed-article:9733861pubmed:issn0022-538Xlld:pubmed
pubmed-article:9733861pubmed:authorpubmed-author:ComptonTTlld:pubmed
pubmed-article:9733861pubmed:authorpubmed-author:HuberM TMTlld:pubmed
pubmed-article:9733861pubmed:issnTypePrintlld:pubmed
pubmed-article:9733861pubmed:volume72lld:pubmed
pubmed-article:9733861pubmed:ownerNLMlld:pubmed
pubmed-article:9733861pubmed:authorsCompleteYlld:pubmed
pubmed-article:9733861pubmed:pagination8191-7lld:pubmed
pubmed-article:9733861pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:meshHeadingpubmed-meshheading:9733861-...lld:pubmed
pubmed-article:9733861pubmed:year1998lld:pubmed
pubmed-article:9733861pubmed:articleTitleThe human cytomegalovirus UL74 gene encodes the third component of the glycoprotein H-glycoprotein L-containing envelope complex.lld:pubmed
pubmed-article:9733861pubmed:affiliationProgram in Cellular and Molecular Biology and Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin 53706-1532, USA.lld:pubmed
pubmed-article:9733861pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9733861pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
family:PF07982.7family:pubmedpubmed-article:9733861lld:pfam
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9733861lld:pubmed
More...