| pubmed-article:9717196 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C0036323 | lld:lifeskim |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C0443224 | lld:lifeskim |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C1327413 | lld:lifeskim |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C1511548 | lld:lifeskim |
| pubmed-article:9717196 | lifeskim:mentions | umls-concept:C1514485 | lld:lifeskim |
| pubmed-article:9717196 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:9717196 | pubmed:dateCreated | 1998-10-26 | lld:pubmed |
| pubmed-article:9717196 | pubmed:abstractText | In this study we neutralized endogenous IL-10 in PBMC from individuals chronically infected with Schistosoma haematobium by using anti-IL-10 MoAbs, and examined the effect and adult worm antigen (AWA)-specific responses in both fresh or cryopreserved cells. Anti-IL-10 alone increased background proliferation of PBMC, but did not augment the AWA-specific responses in either fresh or frozen cells. In freshly isolated PBMC, IFN-gamma production in response to AWA was enhanced significantly in the presence of anti-IL-10. In cryopreserved cells, the augmentation of IFN-gamma in the presence of anti-IL-10 was four-fold less than in the freshly-isolated cells. Neutralization of IL-10 had no effect on IL-4 production. These data show that IL-10 plays a role in specifically down-regulating Th1-but not Th2-type responses and, in contrast to previous reports, anti-IL-10 does not augment proliferation to parasite antigen in chronic schistosomiasis. | lld:pubmed |
| pubmed-article:9717196 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9717196 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9717196 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9717196 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9717196 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9717196 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9717196 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9717196 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9717196 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9717196 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:9717196 | pubmed:issn | 0141-9838 | lld:pubmed |
| pubmed-article:9717196 | pubmed:author | pubmed-author:DeelderA MAM | lld:pubmed |
| pubmed-article:9717196 | pubmed:author | pubmed-author:KremsnerP GPG | lld:pubmed |
| pubmed-article:9717196 | pubmed:author | pubmed-author:GroganJ LJL | lld:pubmed |
| pubmed-article:9717196 | pubmed:author | pubmed-author:YazdanbakhshM... | lld:pubmed |
| pubmed-article:9717196 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9717196 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:9717196 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9717196 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9717196 | pubmed:pagination | 345-9 | lld:pubmed |
| pubmed-article:9717196 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
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| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:meshHeading | pubmed-meshheading:9717196-... | lld:pubmed |
| pubmed-article:9717196 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9717196 | pubmed:articleTitle | The effect of anti-IL-10 on proliferation and cytokine production in human schistosomiasis: fresh versus cryopreserved cells. | lld:pubmed |
| pubmed-article:9717196 | pubmed:affiliation | Department of Parasitology, Leiden University, Lieden University Medical Centre, The Netherlands. | lld:pubmed |
| pubmed-article:9717196 | pubmed:publicationType | Journal Article | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9717196 | lld:pubmed |
