| pubmed-article:9712019 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0017349 | lld:lifeskim |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0225336 | lld:lifeskim |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0001511 | lld:lifeskim |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0017255 | lld:lifeskim |
| pubmed-article:9712019 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:9712019 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9712019 | pubmed:dateCreated | 1998-8-27 | lld:pubmed |
| pubmed-article:9712019 | pubmed:abstractText | NK cells induce MHC class II molecules on the surface of allogeneic endothelial cells in an adhesion-dependent, IFN-gamma-independent manner. Here, we demonstrate that NK cells induce HLA-DR on the surface of a mutant cell line that is defective in IFN-gamma-induced MHC class II expression. RNA analysis in these cells and in a cell line that is defective in class II transactivator (CIITA) demonstrates that NK cell-induced HLA-DR alpha mRNA expression is also CIITA-independent. The Janus kinase-1-deficient cell line U4A expresses HLA-DR alpha mRNA in response to NK cell activation, and HLA-DR alpha promoter constructs transfected into these cells are induced by NK cells but not IFN-gamma. These data indicate that the IFN-gamma-independent component of the target cell HLA-DR expression induced by lymphocyte adhesion uses a signaling pathway that is distinct from the IFN-gamma-dependent mechanism and also suggest that CIITA is not required. | lld:pubmed |
| pubmed-article:9712019 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9712019 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:9712019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9712019 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9712019 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9712019 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:9712019 | pubmed:author | pubmed-author:BendelJ PJP | lld:pubmed |
| pubmed-article:9712019 | pubmed:author | pubmed-author:PardyBB | lld:pubmed |
| pubmed-article:9712019 | pubmed:author | pubmed-author:CollingeMM | lld:pubmed |
| pubmed-article:9712019 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9712019 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:9712019 | pubmed:volume | 161 | lld:pubmed |
| pubmed-article:9712019 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9712019 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9712019 | pubmed:pagination | 1589-93 | lld:pubmed |
| pubmed-article:9712019 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
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| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
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| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:meshHeading | pubmed-meshheading:9712019-... | lld:pubmed |
| pubmed-article:9712019 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9712019 | pubmed:articleTitle | Class II transactivator-independent endothelial cell MHC class II gene activation induced by lymphocyte adhesion. | lld:pubmed |
| pubmed-article:9712019 | pubmed:affiliation | Division of Cardiovascular Medicine, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, CT 06536, USA. mark.collinge@yale.edu | lld:pubmed |
| pubmed-article:9712019 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9712019 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9712019 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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