| pubmed-article:9678719 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C0040052 | lld:lifeskim |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C0025166 | lld:lifeskim |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C0368761 | lld:lifeskim |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C0026985 | lld:lifeskim |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C0018270 | lld:lifeskim |
| pubmed-article:9678719 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:9678719 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:9678719 | pubmed:dateCreated | 1998-8-13 | lld:pubmed |
| pubmed-article:9678719 | pubmed:abstractText | Thrombocytopenia is a frequent feature of myelodysplastic syndromes (MDS) that could be improved by the use of recombinant human megakaryocyte growth and development factor (rHuMGDF). Using short-term liquid cultures and progenitor assays, we have found that rHuMGDF stimulated DNA synthesis and potentiated leukemic cluster growth of bone marrow mononuclear cells in 10/38 MDS cases (26%). Cytogenetically malignant colonies were detectable in rHuMGDF-stimulated cultures (n=3) by fluorescence in situ hybridization. rHuMGDF was able to stimulate CFU-MK formation in 45% of the samples tested. Finally, rHuMGDF-induced blast cell proliferation correlated with elevated expression of c-MPL, previously identified as a bad prognosis factor in MDS. | lld:pubmed |
| pubmed-article:9678719 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9678719 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9678719 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9678719 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:9678719 | pubmed:issn | 0145-2126 | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:CasadevallNN | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:PicardFF | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:DreyfusFF | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:FichelsonSS | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:DupontJ MJM | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:MelloPP | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:BotellaAA | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:GuesnuMM | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:BouscaryDD | lld:pubmed |
| pubmed-article:9678719 | pubmed:author | pubmed-author:Fontenay-Roup... | lld:pubmed |
| pubmed-article:9678719 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9678719 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:9678719 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9678719 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9678719 | pubmed:pagination | 527-35 | lld:pubmed |
| pubmed-article:9678719 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:meshHeading | pubmed-meshheading:9678719-... | lld:pubmed |
| pubmed-article:9678719 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9678719 | pubmed:articleTitle | Analysis of megakaryocyte growth and development factor (thrombopoietin) effects on blast cell and megakaryocyte growth in myelodysplasia. | lld:pubmed |
| pubmed-article:9678719 | pubmed:affiliation | Laboratoire d'Hématologie et INSERM U363 ICGM, Université Paris V, Hôpital Cochin, France. | lld:pubmed |
| pubmed-article:9678719 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9678719 | lld:pubmed |
