| pubmed-article:9667023 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C1533719 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C0152035 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C0042036 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C1257969 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C2936385 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C0008562 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C0205164 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C1522408 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C2699488 | lld:lifeskim |
| pubmed-article:9667023 | lifeskim:mentions | umls-concept:C0286750 | lld:lifeskim |
| pubmed-article:9667023 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9667023 | pubmed:dateCreated | 1998-9-21 | lld:pubmed |
| pubmed-article:9667023 | pubmed:abstractText | Direct chiral resolution of four major flavanones recovered from post-administrative urine of the traditional Chinese medicines Daisaiko-to and Shosaiko-to was achieved by high-performance liquid chromatography (HPLC) on macroporous silica gel coated with cellulose tris(3,5-dimethylphenylcarbamate), Chiralcel OD. Chromatographic conditions were optimized so as to attain satisfactory enantiomeric resolution of the polysubstituted flavanones. Urinary liquiritigenin and naringenin were considerable mixtures of R and S-enantiomers, while S-enantiomers of dihydrowogonin and dihydrooroxylin A were predominantly excreted. Our chiral HPLC techniques can be applied to pharmacokinetical evaluation of the chiral flavanone enantiomers following oral administration of the herbal medicines. | lld:pubmed |
| pubmed-article:9667023 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9667023 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9667023 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9667023 | pubmed:issn | 0269-3879 | lld:pubmed |
| pubmed-article:9667023 | pubmed:author | pubmed-author:HommaMM | lld:pubmed |
| pubmed-article:9667023 | pubmed:author | pubmed-author:OkiCC | lld:pubmed |
| pubmed-article:9667023 | pubmed:author | pubmed-author:MAJJ | lld:pubmed |
| pubmed-article:9667023 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9667023 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:9667023 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9667023 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9667023 | pubmed:pagination | 199-202 | lld:pubmed |
| pubmed-article:9667023 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:meshHeading | pubmed-meshheading:9667023-... | lld:pubmed |
| pubmed-article:9667023 | pubmed:articleTitle | Chiral resolution of four major flavanones in post-administrative urine of Chinese herbal medicines by HPLC on macroporous silica gel coated with cellulose tris(3,5-dimethylphenylcarbamate). | lld:pubmed |
| pubmed-article:9667023 | pubmed:affiliation | Department of Clinical Pharmacology, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Japan. | lld:pubmed |
| pubmed-article:9667023 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9667023 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
