pubmed-article:9493513 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9493513 | lifeskim:mentions | umls-concept:C0376574 | lld:lifeskim |
pubmed-article:9493513 | lifeskim:mentions | umls-concept:C0920283 | lld:lifeskim |
pubmed-article:9493513 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:9493513 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:9493513 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:9493513 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:9493513 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:9493513 | pubmed:dateCreated | 1998-4-13 | lld:pubmed |
pubmed-article:9493513 | pubmed:abstractText | The hepatitis G virus (HGV) is a new member of the Flaviviridae family and has a genomic organization similar to that of hepatitis C virus (HCV). Protein sequence motifs are present suggesting that HGV encodes a serine proteinase, an RNA-dependent RNA polymerase and a helicase. We have cloned and expressed the putative helicase of HGV and have shown that it contains a poly (U)-stimulated NTPase activity and is able to function as a DNA helicase. Preliminary characterization of the HGV helicase activity reveals similarities with other members of the Flaviviridae, but especially with HCV, raising the possibility that HGV could be used as a surrogate virus for the development of therapies against HCV. | lld:pubmed |
pubmed-article:9493513 | pubmed:language | eng | lld:pubmed |
pubmed-article:9493513 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9493513 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9493513 | pubmed:month | Jan | lld:pubmed |
pubmed-article:9493513 | pubmed:issn | 1352-0504 | lld:pubmed |
pubmed-article:9493513 | pubmed:author | pubmed-author:McMillanDD | lld:pubmed |
pubmed-article:9493513 | pubmed:author | pubmed-author:SullivanVV | lld:pubmed |
pubmed-article:9493513 | pubmed:author | pubmed-author:AckrillA MAM | lld:pubmed |
pubmed-article:9493513 | pubmed:author | pubmed-author:LaxtonC DCD | lld:pubmed |
pubmed-article:9493513 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9493513 | pubmed:volume | 5 | lld:pubmed |
pubmed-article:9493513 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9493513 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9493513 | pubmed:pagination | 21-6 | lld:pubmed |
pubmed-article:9493513 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:9493513 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9493513 | pubmed:articleTitle | Expression and characterization of the hepatitis G virus helicase. | lld:pubmed |
pubmed-article:9493513 | pubmed:affiliation | Department of Virology, Roche Discovery Welwyn, Welwyn Garden City, Hertfordshire, UK. | lld:pubmed |
pubmed-article:9493513 | pubmed:publicationType | Journal Article | lld:pubmed |
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