| pubmed-article:9438798 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0023185 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0205653 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0027820 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0021027 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0015328 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0221198 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0443281 | lld:lifeskim |
| pubmed-article:9438798 | lifeskim:mentions | umls-concept:C0439228 | lld:lifeskim |
| pubmed-article:9438798 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:9438798 | pubmed:dateCreated | 1998-3-20 | lld:pubmed |
| pubmed-article:9438798 | pubmed:abstractText | Passive avoidance learning and retention, as well as locomotor and exploratory behaviors, were assessed in rats after intraventricular 192 immunoglobulin G-saporin injections on either Postnatal Day 1 (PND1) or PND7. PND1-lesioned rats were not significantly impaired on acquisition or retention of passive avoidance. PND7-lesioned rats acquired the task slower than controls, but retention was not affected. PND7-lesioned rats were less exploratory than controls and showed reduced wall rearing. Histological analysis of PND1- and PND7-lesioned rats revealed no neuronal degeneration in hippocampus or cortex. There was a marked reduction of choline acetyltransferase (ChAT) activity in the hippocampus, cortex, and septum in the PND7-lesioned rats and a slight but significant ChAT depletion in the cortex of PND1-lesioned rats. These data suggest that the cholinergic system is critical for the learning of passive avoidance and exploratory behaviors in the developing rat. | lld:pubmed |
| pubmed-article:9438798 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9438798 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9438798 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9438798 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:9438798 | pubmed:issn | 0735-7044 | lld:pubmed |
| pubmed-article:9438798 | pubmed:author | pubmed-author:CalamandreiGG | lld:pubmed |
| pubmed-article:9438798 | pubmed:author | pubmed-author:RicceriLL | lld:pubmed |
| pubmed-article:9438798 | pubmed:author | pubmed-author:Berger-Sweene... | lld:pubmed |
| pubmed-article:9438798 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9438798 | pubmed:volume | 111 | lld:pubmed |
| pubmed-article:9438798 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9438798 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9438798 | pubmed:pagination | 1292-302 | lld:pubmed |
| pubmed-article:9438798 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
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| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
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| pubmed-article:9438798 | pubmed:meshHeading | pubmed-meshheading:9438798-... | lld:pubmed |
| pubmed-article:9438798 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9438798 | pubmed:articleTitle | Different effects of postnatal day 1 versus 7 192 immunoglobulin G-saporin lesions on learning, exploratory behaviors, and neurochemistry in juvenile rats. | lld:pubmed |
| pubmed-article:9438798 | pubmed:affiliation | Laboratorio di Fisiopatologia O.S, Istituto Superiore di Sanità, Rome, Italy. | lld:pubmed |
| pubmed-article:9438798 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9438798 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9438798 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:9438798 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
