Linked Life Data

9230191

Source:http://linkedlifedata.com/resource/pubmed/id/9230191

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:9230191rdf:typepubmed:Citationlld:pubmed
pubmed-article:9230191lifeskim:mentionsumls-concept:C0020971lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C0025202lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C0011306lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C0003320lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C1334510lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C0314603lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C0385723lld:lifeskim
pubmed-article:9230191lifeskim:mentionsumls-concept:C0591833lld:lifeskim
pubmed-article:9230191pubmed:issue14lld:pubmed
pubmed-article:9230191pubmed:dateCreated1997-8-7lld:pubmed
pubmed-article:9230191pubmed:abstractTextDendritic cells (DCs) are professional antigen-presenting cells that process and present antigenic peptides and are capable of generating potent T-cell immunity. A murine tumor model was developed to evaluate methods of genetic immunization to the human MART-1/Melan-A (MART-1) melanoma antigen. A poorly immunogenic murine fibrosarcoma line (NFSA) was stably transfected with the MART-1 gene. This transfected tumor [NFSA(MART1)] grows progressively in C3Hf/Kam/Sed (H-2k) mice. Partial protection against a challenge with NFSA(MART1) could be achieved with i.m. injections of a MART-1 expression plasmid or with systemic administration of an adenovirus vector expressing MART-1. However, superior protection was achieved when granulocyte macrophage colony-stimulating factor/interleukin-4-differentiated murine DCs transduced with an adenovirus vector expressing MART-1 were used for immunization. Both partial and complete protection could be achieved with i.v. administration of MART-1-engineered DCs. Splenocytes from immunized mice contained MHC class 1-restricted CTLs specific for MART-1. This preclinical model of genetic immunization supports a therapeutic strategy for human melanoma.lld:pubmed
pubmed-article:9230191pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:languageenglld:pubmed
pubmed-article:9230191pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:citationSubsetIMlld:pubmed
pubmed-article:9230191pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9230191pubmed:statusMEDLINElld:pubmed
pubmed-article:9230191pubmed:monthJullld:pubmed
pubmed-article:9230191pubmed:issn0008-5472lld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:EconomouJ SJSlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:McBrideW HWHlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:LawPPlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:LawG RGRlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:ElyJ SJSlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:RibasAAlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:VollmerC MCMlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:GlaspyJ AJAlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:ChenA YAYlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:DissetteV BVBlld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:ButterfieldL...lld:pubmed
pubmed-article:9230191pubmed:authorpubmed-author:JilaniS MSMlld:pubmed
pubmed-article:9230191pubmed:issnTypePrintlld:pubmed
pubmed-article:9230191pubmed:day15lld:pubmed
pubmed-article:9230191pubmed:volume57lld:pubmed
pubmed-article:9230191pubmed:ownerNLMlld:pubmed
pubmed-article:9230191pubmed:authorsCompleteYlld:pubmed
pubmed-article:9230191pubmed:pagination2865-9lld:pubmed
pubmed-article:9230191pubmed:dateRevised2010-11-18lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:meshHeadingpubmed-meshheading:9230191-...lld:pubmed
pubmed-article:9230191pubmed:year1997lld:pubmed
pubmed-article:9230191pubmed:articleTitleGenetic immunization for the melanoma antigen MART-1/Melan-A using recombinant adenovirus-transduced murine dendritic cells.lld:pubmed
pubmed-article:9230191pubmed:affiliationDivision of Surgical Oncology, University of California Los Angeles Medical Center, 90024, USA.lld:pubmed
pubmed-article:9230191pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9230191pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:9230191pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9230191lld:pubmed