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pubmed-article:9214675pubmed:abstractTextRecent recognition that a predisposition to prostate cancer can be inherited has led to a search for specific genes associated with the disease. Through a study of families with three or more affected first-degree relatives, a region on the long arm of chromosome 1 (i.e., 1q24-25) has been tentatively identified as containing a gene, HPC1, involved in the development of hereditary prostate cancer. Confirmation of this finding is needed, however, before attempts are made to isolate and characterize the putative HPC1 gene.lld:pubmed
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pubmed-article:9214675pubmed:articleTitleProstate cancer susceptibility locus on chromosome 1q: a confirmatory study.lld:pubmed
pubmed-article:9214675pubmed:affiliationDepartment of Internal Medicine, University of Michigan Medical School, and Ann Arbor Veterans Affairs Medical Center, USA. kcooney@umich.edulld:pubmed
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