| pubmed-article:9212080 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C0228088 | lld:lifeskim |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C0037083 | lld:lifeskim |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C1621574 | lld:lifeskim |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C0597484 | lld:lifeskim |
| pubmed-article:9212080 | lifeskim:mentions | umls-concept:C0444498 | lld:lifeskim |
| pubmed-article:9212080 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:9212080 | pubmed:dateCreated | 1997-8-1 | lld:pubmed |
| pubmed-article:9212080 | pubmed:abstractText | The role of sodium-calcium exchanger in calcium homeostasis in Bergmann glial cells in situ was investigated by monitoring cytoplasmic calcium ([Ca2+]i) and sodium ([Na+]i) concentrations. The [Ca2+]i and [Na+]i transients were measured either separately by using fluorescent indicators fura-2 and SBFI, respectively, or simultaneously using the indicators fluo-3 and SBFI. Since the removal of extracellular Na+ induced a relatively small (approximately 50 nM) elevation of [Ca2+]i, the Na+/Ca2+ exchanger seems to play a minor role in regulation of resting [Ca2+]i. In contrast, kainate-triggered [Ca2+]i increase was significantly suppressed by lowering of the extracellular Na+ concentration ([Na+]o). In addition, manipulations with [Na+]o dramatically affected the recovery of the kainate-induced [Ca2+]i transients. Simultaneous recordings of [Ca2+]i and [Na+]i revealed that kainate-evoked [Ca2+]i transients were accompanied with an increase in [Na+]i. Moreover, kainate induced significantly larger [Ca2+]i and smaller [Na+]i transients under current-clamp conditions as compared to those recorded when the membrane voltage was clamped at -70 mV. The above results demonstrate that the Na(+)-Ca2+ exchanger is operative in Bergmann glial cells in situ and is able to modulate dynamically the amplitude and kinetics of [Ca2+]i signals associated with an activation of ionotropic glutamate receptors. | lld:pubmed |
| pubmed-article:9212080 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9212080 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9212080 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9212080 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:9212080 | pubmed:issn | 0892-6638 | lld:pubmed |
| pubmed-article:9212080 | pubmed:author | pubmed-author:KettenmannHH | lld:pubmed |
| pubmed-article:9212080 | pubmed:author | pubmed-author:VerkhratskyAA | lld:pubmed |
| pubmed-article:9212080 | pubmed:author | pubmed-author:KirischukSS | lld:pubmed |
| pubmed-article:9212080 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9212080 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:9212080 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9212080 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9212080 | pubmed:pagination | 566-72 | lld:pubmed |
| pubmed-article:9212080 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9212080 | pubmed:meshHeading | pubmed-meshheading:9212080-... | lld:pubmed |
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| pubmed-article:9212080 | pubmed:meshHeading | pubmed-meshheading:9212080-... | lld:pubmed |
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| pubmed-article:9212080 | pubmed:meshHeading | pubmed-meshheading:9212080-... | lld:pubmed |
| pubmed-article:9212080 | pubmed:meshHeading | pubmed-meshheading:9212080-... | lld:pubmed |
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| pubmed-article:9212080 | pubmed:meshHeading | pubmed-meshheading:9212080-... | lld:pubmed |
| pubmed-article:9212080 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9212080 | pubmed:articleTitle | Na+/Ca2+ exchanger modulates kainate-triggered Ca2+ signaling in Bergmann glial cells in situ. | lld:pubmed |
| pubmed-article:9212080 | pubmed:affiliation | Max-Delbruck-Centre for Molecular Medicine, Berlin-Buch, Germany. | lld:pubmed |
| pubmed-article:9212080 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9212080 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:9212080 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9212080 | lld:pubmed |
