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pubmed-article:9120965pubmed:abstractTextA recent demonstration of peripheral opioid receptors suggested the possibility of delivering morphine locally into the bladder after reimplantation for ameliorating the discomfort of postoperative bladder irritation with spasms. Since we do not use bladder drainage after reimplantation, dripping a morphine solution into the bladder permits contact with the urothelium between voidings. A pilot trial using an arbitrary concentration was subjectively beneficial for treating these patients postoperatively. We now report a prospective randomized study evaluating the effectiveness and dosage of various concentrations of intravesical morphine infusions.lld:pubmed
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pubmed-article:9120965pubmed:articleTitleIntravesical morphine analgesia after bladder surgery.lld:pubmed
pubmed-article:9120965pubmed:affiliationDepartment of Urology, Children's Hospital of Philadelphia, Pennsylvania, USA.lld:pubmed
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