Linked Life Data

8989656

Source:http://linkedlifedata.com/resource/pubmed/id/8989656

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:8989656rdf:typepubmed:Citationlld:pubmed
pubmed-article:8989656lifeskim:mentionsumls-concept:C0205653lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0025914lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0026809lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0018497lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0039062lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0021516lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0439825lld:lifeskim
pubmed-article:8989656lifeskim:mentionsumls-concept:C0205198lld:lifeskim
pubmed-article:8989656pubmed:issue3lld:pubmed
pubmed-article:8989656pubmed:dateCreated1997-3-28lld:pubmed
pubmed-article:8989656pubmed:abstractTextUltrastructural investigation of the gamma-aminobutyric acid (GABA) component of the inner spiral bundle in adolescent mice revealed a pathway of glutamic acid decarboxylase (GAD)-positive and -negative fibers and vesiculated endings that contact inner hair cells and their afferents through a complex of axosomatic and axodendritic synapses. Ultrastructural details were investigated by using conventional electron microscopy. Several synaptic arrangements were observed: Main axosomatic synapses form between vesiculated endings and individual or adjoining inner hair cells (interreceptor synapses). Spinous synapses form on long, spinelike processes that protrude from inner hair cells to reach distant efferent endings. The efferent endings associate with inner hair cells and their synaptic afferents through compound synapses-serial, "converging," and triadic-otherwise characteristic of sensory relay nuclei. Serial synapses form by the sequential presynaptic alignment of the efferent-->receptor-->afferent components. Converging synapses result from the simultaneous apposition of a receptor ribbon synapse and a presynaptic efferent terminal on a recipient afferent dendrite. Triadic synapses comprise a vesiculated efferent ending in contact with an inner hair cell and with its synaptic afferent. Additionally, efferent endings may form simple axodendritic and axoaxonal synapses with GAD-negative vesiculated endings. The combination of different synaptic arrangements leads to short chains of compound synapses. It is assumed that these synaptic patterns seen in the adolescent mouse represent adult synaptology. The patterns of synaptic connectivity suggest an integrative role for the GABA/GAD lateral efferent system, and imply its involvement in the pre- and postsynaptic modulation of auditory signals.lld:pubmed
pubmed-article:8989656pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8989656pubmed:languageenglld:pubmed
pubmed-article:8989656pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8989656pubmed:citationSubsetIMlld:pubmed
pubmed-article:8989656pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8989656pubmed:statusMEDLINElld:pubmed
pubmed-article:8989656pubmed:monthJanlld:pubmed
pubmed-article:8989656pubmed:issn0021-9967lld:pubmed
pubmed-article:8989656pubmed:authorpubmed-author:SobkowiczH...lld:pubmed
pubmed-article:8989656pubmed:authorpubmed-author:SlapnickS MSMlld:pubmed
pubmed-article:8989656pubmed:authorpubmed-author:AugustB KBKlld:pubmed
pubmed-article:8989656pubmed:authorpubmed-author:NiteckaL MLMlld:pubmed
pubmed-article:8989656pubmed:issnTypePrintlld:pubmed
pubmed-article:8989656pubmed:day20lld:pubmed
pubmed-article:8989656pubmed:volume377lld:pubmed
pubmed-article:8989656pubmed:ownerNLMlld:pubmed
pubmed-article:8989656pubmed:authorsCompleteYlld:pubmed
pubmed-article:8989656pubmed:pagination423-42lld:pubmed
pubmed-article:8989656pubmed:dateRevised2007-11-15lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:meshHeadingpubmed-meshheading:8989656-...lld:pubmed
pubmed-article:8989656pubmed:year1997lld:pubmed
pubmed-article:8989656pubmed:articleTitleCompound synapses within the GABAergic innervation of the auditory inner hair cells in the adolescent mouse.lld:pubmed
pubmed-article:8989656pubmed:affiliationDepartment of Neurology, University of Wisconsin, Madison 53706, USA. hmsobkow@facstaff.wisc.edulld:pubmed
pubmed-article:8989656pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8989656pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8989656lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8989656lld:pubmed