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pubmed-article:8941012pubmed:abstractTextCongenital hypertrophy of the retinal pigment epithelium (CHRPE) is the most common extracolonic manifestation of familial adenomatous polyposis (FAP) and is an early clinical marker of the disease. It seems to be correlated with the position of constitutional mutations of the adenomatous polyposis coli (APC) gene.lld:pubmed
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pubmed-article:8941012pubmed:articleTitleCongenital hypertrophy of the retinal pigment epithelium in familial adenomatous polyposis. Novel criteria of assessment and correlations with constitutional adenomatous polyposis coli gene mutations.lld:pubmed
pubmed-article:8941012pubmed:affiliationDipartimento di Fisiopatologia Clinica, Universita di Firenze, Italy.lld:pubmed
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