| pubmed-article:8782071 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C0027061 | lld:lifeskim |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C1179956 | lld:lifeskim |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C0205191 | lld:lifeskim |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8782071 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8782071 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:8782071 | pubmed:dateCreated | 1996-11-27 | lld:pubmed |
| pubmed-article:8782071 | pubmed:abstractText | Cardiomyocytes of chronic hibernating myocardium are known to undergo structural changes, indicative of dedifferentiation. Amongst these are changes in nuclear shape and chromatin distribution. Nuclear A-type lamins are known to be expressed in a differentiation-related fashion and to contribute to nuclear integrity and chromatin organization. Lamin expression was investigated with immunocytochemical staining procedures in biopsies from patients with chronic hibernating myocardium. The expression of A-type (lamin A and C) were shown to be downregulated during hibernation, while lamin B2 remained present in hibernating cardiomyocytes in a way similar to embryonic muscle cells. All heart muscle cells were shown to be negative for lamin B1. The absence of A-type lamins in chronic hibernating cardiomyocytes could be taken as an additional argument for the dedifferentiation state of these cells. The absence of A-type lamins was accompanied by dispersion of the nuclear heterochromatin, in a way similar to nuclei of embryonic cardiomyocytes. | lld:pubmed |
| pubmed-article:8782071 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8782071 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8782071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8782071 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8782071 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8782071 | pubmed:issn | 0022-2828 | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:BorgersMM | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:ThonéFF | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:FlamengWW | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:RamaekersF... | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:BroersJ LJL | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:van EysG JGJ | lld:pubmed |
| pubmed-article:8782071 | pubmed:author | pubmed-author:AusmaJJ | lld:pubmed |
| pubmed-article:8782071 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8782071 | pubmed:volume | 28 | lld:pubmed |
| pubmed-article:8782071 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8782071 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8782071 | pubmed:pagination | 1297-305 | lld:pubmed |
| pubmed-article:8782071 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
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| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:meshHeading | pubmed-meshheading:8782071-... | lld:pubmed |
| pubmed-article:8782071 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8782071 | pubmed:articleTitle | Nuclear lamin expression in chronic hibernating myocardium in man. | lld:pubmed |
| pubmed-article:8782071 | pubmed:affiliation | Department of Molecular Cell Biology & Genetics, Maastricht, University of Limburg, The Netherlands. | lld:pubmed |
| pubmed-article:8782071 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8782071 | lld:pubmed |
