| pubmed-article:8781234 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8781234 | lifeskim:mentions | umls-concept:C0014181 | lld:lifeskim |
| pubmed-article:8781234 | lifeskim:mentions | umls-concept:C0042567 | lld:lifeskim |
| pubmed-article:8781234 | lifeskim:mentions | umls-concept:C0246305 | lld:lifeskim |
| pubmed-article:8781234 | lifeskim:mentions | umls-concept:C0445356 | lld:lifeskim |
| pubmed-article:8781234 | pubmed:issue | 5282 | lld:pubmed |
| pubmed-article:8781234 | pubmed:dateCreated | 1996-10-11 | lld:pubmed |
| pubmed-article:8781234 | pubmed:abstractText | Progress through the cell cycle is governed by the cyclin-dependent kinases (CDKs), the activation of which requires phosphorylation by the CDK-activating kinase (CAK). In vertebrates, CAK is a trimeric enzyme containing CDK7, cyclin H, and MAT1. CAK from the budding yeast Saccharomyces cerevisiae was identified as an unusual 44-kilodalton protein kinase, Cak1, that is only distantly related to CDKs. Cak1 accounted for most CAK activity in yeast cell lysates, and its activity was constant throughout the cell cycle. The CAK1 gene was essential for cell viability. Thus, the major CAK in S. cerevisiae is distinct from the vertebrate enzyme, suggesting that budding yeast and vertebrates may have evolved different mechanisms of CDK activation. | lld:pubmed |
| pubmed-article:8781234 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8781234 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8781234 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8781234 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:8781234 | pubmed:issn | 0036-8075 | lld:pubmed |
| pubmed-article:8781234 | pubmed:author | pubmed-author:MorganD ODO | lld:pubmed |
| pubmed-article:8781234 | pubmed:author | pubmed-author:TempstPP | lld:pubmed |
| pubmed-article:8781234 | pubmed:author | pubmed-author:FarrellAA | lld:pubmed |
| pubmed-article:8781234 | pubmed:author | pubmed-author:Erdjument-Bro... | lld:pubmed |
| pubmed-article:8781234 | pubmed:author | pubmed-author:EspinozaF HFH | lld:pubmed |
| pubmed-article:8781234 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8781234 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:8781234 | pubmed:volume | 273 | lld:pubmed |
| pubmed-article:8781234 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8781234 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8781234 | pubmed:pagination | 1714-7 | lld:pubmed |
| pubmed-article:8781234 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:meshHeading | pubmed-meshheading:8781234-... | lld:pubmed |
| pubmed-article:8781234 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8781234 | pubmed:articleTitle | A cyclin-dependent kinase-activating kinase (CAK) in budding yeast unrelated to vertebrate CAK. | lld:pubmed |
| pubmed-article:8781234 | pubmed:affiliation | Department of Physiology, University of California, San Francisco, 94143-0444, USA. | lld:pubmed |
| pubmed-article:8781234 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8781234 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8781234 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:8781234 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8781234 | lld:pubmed |
