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pubmed-article:8777203pubmed:abstractTextTotal lymphoid irradiation (640 cGy) was given to 19 heart and 1 heart-lung recipients on maintenance triple therapy at a mean of 4.9 +/- 4 months after transplantation (range 46 to 519 days). Mean number of treated rejection episodes before, during, and after total lymphoid irradiation was 6.4 +/- 1.7, 0.8 +/- 1.2, and 1.2 +/- 1.3 episodes per patient, respectively. During total lymphoid irradiation, 37% had at least one episode of rejection requiring treatment; after total lymphoid irradiation, 42% had no further rejection episodes, 21% had one further episode, and 37% had 2 or more episodes. Metastatic squamous cell carcinoma in one patient and coronary artery disease in three of five patients studied to date is of concern and requires longer follow-up.lld:pubmed
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pubmed-article:8777203pubmed:articleTitleClinical heart transplantation. Total lymphoid irradiation for resistant rejection after heart transplantation: only moderate success medium-term.lld:pubmed
pubmed-article:8777203pubmed:affiliationHeart and Lung Transplant Unit, Victor Chang Research Institute, Darlinghurst, Sydney, Australia.lld:pubmed
pubmed-article:8777203pubmed:publicationTypeJournal Articlelld:pubmed