| pubmed-article:8756296 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8756296 | lifeskim:mentions | umls-concept:C1425287 | lld:lifeskim |
| pubmed-article:8756296 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:8756296 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:8756296 | lifeskim:mentions | umls-concept:C2752630 | lld:lifeskim |
| pubmed-article:8756296 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:8756296 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:8756296 | pubmed:dateCreated | 1996-9-20 | lld:pubmed |
| pubmed-article:8756296 | pubmed:abstractText | The Caenorhabditis elegans gene lin-29 is required for the terminal differentiation of the lateral hypodermal seam cells during the larval-to-adult molt. We find that lin-29 protein accumulates in the nuclei of these cells, consistent with its predicted role as a zinc finger transcription factor. The earliest detectable LIN-29 accumulation in seam cell nuclei is during the last larval stage (L4), following the final seam cell division, which occurs during the L3-to-L4 molt. LIN-29 accumulates in all hypodermal nuclei during the L4 stage. The time of LIN-29 appearance in the hypodermis is controlled by the heterochronic gene pathway: LIN-29 accumulates in the hypodermis abnormally early, during the third larval stage, in loss-of-function lin-14, lin-28 and lin-42 mutants, and fails to accumulate in hypodermis of lin-4 mutants. LIN-29 also accumulates stage-specifically in the nuclei of a variety of non-hypodermal cells during development. Its accumulation is dependent upon the upstream heterochronic genes in some, but not all, of these non-hypodermal cells. | lld:pubmed |
| pubmed-article:8756296 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8756296 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8756296 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8756296 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8756296 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8756296 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:8756296 | pubmed:issn | 0950-1991 | lld:pubmed |
| pubmed-article:8756296 | pubmed:author | pubmed-author:LeeKK | lld:pubmed |
| pubmed-article:8756296 | pubmed:author | pubmed-author:RougvieA EAE | lld:pubmed |
| pubmed-article:8756296 | pubmed:author | pubmed-author:BettingerJ... | lld:pubmed |
| pubmed-article:8756296 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8756296 | pubmed:volume | 122 | lld:pubmed |
| pubmed-article:8756296 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8756296 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8756296 | pubmed:pagination | 2517-27 | lld:pubmed |
| pubmed-article:8756296 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8756296 | pubmed:meshHeading | pubmed-meshheading:8756296-... | lld:pubmed |
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| pubmed-article:8756296 | pubmed:meshHeading | pubmed-meshheading:8756296-... | lld:pubmed |
| pubmed-article:8756296 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8756296 | pubmed:articleTitle | Stage-specific accumulation of the terminal differentiation factor LIN-29 during Caenorhabditis elegans development. | lld:pubmed |
| pubmed-article:8756296 | pubmed:affiliation | Department of Genetics and Cell Biology, University of Minnesota, St Paul 55108, USA. | lld:pubmed |
| pubmed-article:8756296 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8756296 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8756296 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:8756296 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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