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pubmed-article:8579053pubmed:abstractTextWe report a case of severe priapism occurring in a patient with an unstable hemoglobin, Hb Olmsted (beta 141 Leu-->Arg) This is a rare hemoglobin variant, which until now has been reported only once. The clinical course of the 12-year-old boy was characterized by severe hemolytic anemia leading to splenectomy and cholecystectomy at the of 3.5 years. The priapism occurred 8 years after splenectomy, during a hemolytic febrile episode and required aspiration of the corpora cavernosa. This report raises the question of the benefit of splenectomy in patients suffering from a chronic hemolytic anemia such as that due to an unstable hemoglobin. This treatment lowers the frequency and the severity of acute hemolytic attacks, but several cases of vascular complications have been reported after splenectomy.lld:pubmed
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pubmed-article:8579053pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:8579053pubmed:articleTitlePriapism following splenectomy in an unstable hemoglobin: hemoglobin Olmsted beta 141 (H19) Leu-->Arg.lld:pubmed
pubmed-article:8579053pubmed:affiliationCentre d'Enseignement et de Recherche in Génétique Médicale, CHU-Timone, Marseille, France.lld:pubmed
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