| pubmed-article:8569681 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C0027923 | lld:lifeskim |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C0080103 | lld:lifeskim |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
| pubmed-article:8569681 | lifeskim:mentions | umls-concept:C0349590 | lld:lifeskim |
| pubmed-article:8569681 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8569681 | pubmed:dateCreated | 1996-3-7 | lld:pubmed |
| pubmed-article:8569681 | pubmed:abstractText | The 293-amino acid mt A-1 ORF of the A mating-type idiomorph of Neurospora crassa is multifunctional. It confers A mating identity and is responsible for heterokaryon incompatibility. The goal of this study was to dissect the functional regions of mt A-1. New mutants of mt A-1 selected for loss of the incompatibility function were obtained. One new mutant, A(m)99, was partially fertile as a maternal parent. This is the first time that fertility and incompatibility functions have been separated for the A idiomorph. In this mutant, the mt A-1 ORF is truncated after the first 85 amino acids, indicating that this N-terminal region is minimally sufficient for female fertility. A series of deletion constructs and frameshift alleles of mt A-1 was obtained and tested for male-mating activity and vegetative incompatibility in transformation experiments. These experiments showed that a region from position 1 to 111 is sufficient to confer incompatibility, while amino acids from position 1 to 227 are required for mating activity. A transcriptional analysis of mt A-1 showed that the mRNA is expressed both before and after fertilization. This, together with the phenotype of the A(m)99 mutant, suggests a post-fertilization function for mt A-1. | lld:pubmed |
| pubmed-article:8569681 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8569681 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8569681 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8569681 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8569681 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8569681 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:8569681 | pubmed:issn | 0026-8925 | lld:pubmed |
| pubmed-article:8569681 | pubmed:author | pubmed-author:GriffithsA... | lld:pubmed |
| pubmed-article:8569681 | pubmed:author | pubmed-author:GlassN LNL | lld:pubmed |
| pubmed-article:8569681 | pubmed:author | pubmed-author:StenbergLL | lld:pubmed |
| pubmed-article:8569681 | pubmed:author | pubmed-author:SogoS GSG | lld:pubmed |
| pubmed-article:8569681 | pubmed:author | pubmed-author:SaupeSS | lld:pubmed |
| pubmed-article:8569681 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8569681 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:8569681 | pubmed:volume | 250 | lld:pubmed |
| pubmed-article:8569681 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8569681 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8569681 | pubmed:pagination | 115-22 | lld:pubmed |
| pubmed-article:8569681 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
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| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
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| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
| pubmed-article:8569681 | pubmed:meshHeading | pubmed-meshheading:8569681-... | lld:pubmed |
| pubmed-article:8569681 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8569681 | pubmed:articleTitle | The molecular nature of mutations in the mt A-1 gene of the Neurospora crassa A idiomorph and their relation to mating-type function. | lld:pubmed |
| pubmed-article:8569681 | pubmed:affiliation | Department of Botany, University of British Columbia, Vancouver, Canada. | lld:pubmed |
| pubmed-article:8569681 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8569681 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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