pubmed-article:8548074 | pubmed:abstractText | Data of in vitro and in vivo investigations of antimicrobial activity of preparation K carried out both by the authors and by other researchers and pharmacological properties of this preparation have been summarized. Preparation K has been obtained from medicinal plant of the Asteraceae family. It is a natural composition of two antibiotics and of a number of minor compounds. The preparation possesses a wide spectrum of biological action. It is antimicrobially active against gram-positive bacteria, some species of gram-negative bacteria, fungi-dermatophytes including antibiotic-resistant strains. It is not toxic for animals, stimulates some defensive reactions of macroorganism, has immunomodulating, anti-inflammatory, anti-exudative, keratolytic properties. Preparation K is efficient for treatment of experimental mycoses of animals and is clinically tested as a local agent for treatment of dermatomycoses. | lld:pubmed |