| pubmed-article:8530627 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8530627 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:8530627 | lifeskim:mentions | umls-concept:C0001779 | lld:lifeskim |
| pubmed-article:8530627 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:8530627 | lifeskim:mentions | umls-concept:C0011854 | lld:lifeskim |
| pubmed-article:8530627 | lifeskim:mentions | umls-concept:C0015608 | lld:lifeskim |
| pubmed-article:8530627 | lifeskim:mentions | umls-concept:C0080103 | lld:lifeskim |
| pubmed-article:8530627 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:8530627 | pubmed:dateCreated | 1996-1-31 | lld:pubmed |
| pubmed-article:8530627 | pubmed:abstractText | The international community of diabetologists is rapidly becoming involved in intervention trials aimed at preventing insulin-dependent diabetes in high risk relatives. Whereas age and relationship to a proband with insulin-dependent diabetes mellitus interacting with detected islet cell autoantibodies (ICA) are risk factors, their independent contribution to that risk remains unclear. In a prospective study of 6851 nondiabetic relatives of 2742 probands conducted between 1979-1993, we found age, but not relationship, to be a dramatic risk variable in ICA-positive persons as estimated by the Cox regression model. The 5-yr risk of insulin-dependent diabetes mellitus was 66% for those found to have ICA detectable before age 10 yr, falling progressively to less than 16% for ICA-positive relatives over age 40 yr. In ICA-negative relatives, age and relationship are independent prognostic variables. | lld:pubmed |
| pubmed-article:8530627 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8530627 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8530627 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8530627 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8530627 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8530627 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:8530627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8530627 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8530627 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8530627 | pubmed:issn | 0021-972X | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:SchwartzSS | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:MaclarenN KNK | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:RileyW JWJ | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:MaloneJJ | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:KrischerJ PJP | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:CantorA BAB | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:SchatzD ADA | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:QuattrinTT | lld:pubmed |
| pubmed-article:8530627 | pubmed:author | pubmed-author:CuthbertsonD... | lld:pubmed |
| pubmed-article:8530627 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8530627 | pubmed:volume | 80 | lld:pubmed |
| pubmed-article:8530627 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8530627 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8530627 | pubmed:pagination | 3739-43 | lld:pubmed |
| pubmed-article:8530627 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:meshHeading | pubmed-meshheading:8530627-... | lld:pubmed |
| pubmed-article:8530627 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8530627 | pubmed:articleTitle | Age and family relationship accentuate the risk of insulin-dependent diabetes mellitus (IDDM) in relatives of patients with IDDM. | lld:pubmed |
| pubmed-article:8530627 | pubmed:affiliation | Department of Pediatrics, University of South Florida, Tampa 33612, USA. | lld:pubmed |
| pubmed-article:8530627 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8530627 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
