| pubmed-article:8510520 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0023779 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0017861 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0041004 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0724624 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0022702 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C1518896 | lld:lifeskim |
| pubmed-article:8510520 | lifeskim:mentions | umls-concept:C0014020 | lld:lifeskim |
| pubmed-article:8510520 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:8510520 | pubmed:dateCreated | 1993-7-9 | lld:pubmed |
| pubmed-article:8510520 | pubmed:abstractText | Several studies have reported that parenteral lipid emulsions containing medium-chain triglycerides (MCT) and structured lipids (SL) are better utilized than those containing long-chain triglycerides (LCT). The objective of this study was to test the hypothesis that parenteral LCT require more extensive modification via hydrolysis and reesterification (triglyceride-free fatty acid [TG-FFA] recycling) for effective utilization, whereas MCT and SL do not. As an index of TG-FFA cycling activity, we measured glycerol and palmitate kinetics in rats (204 to 243 g) fed parenterally one of three isocaloric (250 kcal/kg/d) isonitrogenous (1.5 g N/kg/d) diets with half of the nonprotein energy from glucose and the rest from either LCT, LCT plus MCT, or SL for 5 days. Two experiments were performed. On day 5, rats were given a 7-to 8-hour infusion of either 5H2 Glycerol and 1-14C Palmitate bound to albumin to measure palmitate and glycerol kinetics (experiment 1), or U-13C glucose to determine the proportion of endogenous glycerol production derived from glucose (experiment 2). Data are presented as means +/- SEM. Endogenous glycerol production was significantly higher with LCT (11.33 +/- 2.89 mmol/kg/h) than with SL (2.91 +/- 0.62 mmol/kg/h). The value for the physical mixture of LCT plus MCT (5.46 +/- 1.29 mmol/kg/h) fell midway between that for LCT and SL (P = NS). There were no significant differences in palmitate kinetics or oxidation. The increased glycerol production is due to the mobilization of endogenous triglyceride and is consistent with a higher rate of TG-FFA cycling being involved in the metabolism of LCT than of SL.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:8510520 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8510520 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8510520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8510520 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8510520 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8510520 | pubmed:issn | 0026-0495 | lld:pubmed |
| pubmed-article:8510520 | pubmed:author | pubmed-author:SteinT PTP | lld:pubmed |
| pubmed-article:8510520 | pubmed:author | pubmed-author:DreweRR | lld:pubmed |
| pubmed-article:8510520 | pubmed:author | pubmed-author:SchluterM DMD | lld:pubmed |
| pubmed-article:8510520 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8510520 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:8510520 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8510520 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8510520 | pubmed:pagination | 743-8 | lld:pubmed |
| pubmed-article:8510520 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:meshHeading | pubmed-meshheading:8510520-... | lld:pubmed |
| pubmed-article:8510520 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8510520 | pubmed:articleTitle | Glycerol kinetics with parenteral lipid emulsions (long-chain triglycerides, medium-chain triglycerides, and structured lipids) in rats. | lld:pubmed |
| pubmed-article:8510520 | pubmed:affiliation | Department of Surgery, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Camden 08103. | lld:pubmed |
| pubmed-article:8510520 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8510520 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
