pubmed-article:8485955 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8485955 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:8485955 | lifeskim:mentions | umls-concept:C0020615 | lld:lifeskim |
pubmed-article:8485955 | lifeskim:mentions | umls-concept:C0205082 | lld:lifeskim |
pubmed-article:8485955 | lifeskim:mentions | umls-concept:C0026538 | lld:lifeskim |
pubmed-article:8485955 | lifeskim:mentions | umls-concept:C0376249 | lld:lifeskim |
pubmed-article:8485955 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:8485955 | pubmed:dateCreated | 1993-6-4 | lld:pubmed |
pubmed-article:8485955 | pubmed:abstractText | To estimate the frequency and morbidity of insulin-induced hypoglycaemia, a retrospective survey was undertaken of the frequency of severe hypoglycaemia in 600 randomly selected patients with insulin-treated diabetes who were attending a large diabetic outpatient clinic in a teaching hospital. The resulting morbidity (hypoglycaemia-related injuries, convulsions, and road traffic accidents) was ascertained in 302 patients. One hundred and seventy-five (29.2%) of the 600 patients reported a total of 964 episodes of severe hypoglycaemia in the preceding year, giving an overall frequency for the group of 1.60 episodes patient-1year-1. The frequency of severe hypoglycaemia which was documented in 544 Type 1 (ketosis prone) diabetic patients was double that observed in a subgroup of 56 Type 2 diabetic patients who were being treated with insulin (1.70 vs 0.73 episodes patient-1year-1). In the subset of 302 patients, those who had experienced severe hypoglycaemia had greater morbidity associated with an estimated rate of injury of 0.04 injuries person-1year-1. Twenty (6.6%) patients reported a total of 37 convulsions associated with hypoglycaemia, 5 of which had occurred in the preceding year (0.02 convulsions person-1year-1). Five patients reported road traffic accidents in the preceding year which had been caused by hypoglycaemia. The only reliable predictors of severe hypoglycaemia were a history of previous severe hypoglycaemia (p < 0.001), a history of hypoglycaemia-related injury (p < 0.001) or convulsion (p < 0.001), and the duration of insulin therapy (p < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
pubmed-article:8485955 | pubmed:language | eng | lld:pubmed |
pubmed-article:8485955 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8485955 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8485955 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8485955 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8485955 | pubmed:month | Apr | lld:pubmed |
pubmed-article:8485955 | pubmed:issn | 0742-3071 | lld:pubmed |
pubmed-article:8485955 | pubmed:author | pubmed-author:MacLeodK MKM | lld:pubmed |
pubmed-article:8485955 | pubmed:author | pubmed-author:FrierB MBM | lld:pubmed |
pubmed-article:8485955 | pubmed:author | pubmed-author:HepburnD ADA | lld:pubmed |
pubmed-article:8485955 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8485955 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:8485955 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8485955 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8485955 | pubmed:pagination | 238-45 | lld:pubmed |
pubmed-article:8485955 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:8485955 | pubmed:year | 1993 | lld:pubmed |
pubmed-article:8485955 | pubmed:articleTitle | Frequency and morbidity of severe hypoglycaemia in insulin-treated diabetic patients. | lld:pubmed |
pubmed-article:8485955 | pubmed:affiliation | Department of Diabetes, Royal Infirmary, Edinburgh, UK. | lld:pubmed |
pubmed-article:8485955 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8485955 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:8485955 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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