| pubmed-article:8480681 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C1708335 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0021641 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0042874 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0332161 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0178602 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:8480681 | lifeskim:mentions | umls-concept:C0205464 | lld:lifeskim |
| pubmed-article:8480681 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8480681 | pubmed:dateCreated | 1993-5-27 | lld:pubmed |
| pubmed-article:8480681 | pubmed:abstractText | Ten control (healthy) subjects and 15 non-insulin-dependent diabetics underwent an oral glucose-tolerance test and a euglycemic hyperinsulinemic glucose clamp before and after vitamin E supplementation (900 mg/d for 4 mo). In control subjects (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E reduced the area under the curve for glucose (344 +/- 21 vs 287 +/- 13 mmol.L-1 x min-1; P < 0.05) and increased total body glucose disposal (39.0 +/- 0.3 vs 47.6 +/- 0.4 mumol.kg lean body mass-1 x min-1; P < 0.05) and non-oxidative glucose metabolism (23.4 +/- 0.2 vs 30.8 +/- 0.3 mumol.kg lean body mass-1 x min-1; P < 0.05). In diabetics (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E supplementation reduced glucose area under the curve (614 +/- 129 vs 544 +/- 98 mmol.L-1 x min-1; P < 0.03) and increased glucose disappearance (19.4 +/- 0.4 vs 26.4 +/- 0.7 mumol.kg lean body mass-1.min-1; P < 0.03), total glucose disposal (19.0 +/- 0.7 vs 28.1 +/- 0.4 mumol.kg lean body mass-1 x min-1; P < 0.02), and nonoxidative glucose metabolism (8.5 +/- 0.3 vs 13.9 +/- 0.3 mumol.kg lean body mass-1 x min-1; P < 0.02). Therefore we conclude that administration of pharmacologic doses of vitamin E is a useful tool to reduce oxidative stress and improve insulin action. | lld:pubmed |
| pubmed-article:8480681 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8480681 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8480681 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8480681 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8480681 | pubmed:month | May | lld:pubmed |
| pubmed-article:8480681 | pubmed:issn | 0002-9165 | lld:pubmed |
| pubmed-article:8480681 | pubmed:author | pubmed-author:D'OnofrioFF | lld:pubmed |
| pubmed-article:8480681 | pubmed:author | pubmed-author:VarricchioMM | lld:pubmed |
| pubmed-article:8480681 | pubmed:author | pubmed-author:GiuglianoDD | lld:pubmed |
| pubmed-article:8480681 | pubmed:author | pubmed-author:CerielloAA | lld:pubmed |
| pubmed-article:8480681 | pubmed:author | pubmed-author:PaolissoGG | lld:pubmed |
| pubmed-article:8480681 | pubmed:author | pubmed-author:D'AmoreAA | lld:pubmed |
| pubmed-article:8480681 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8480681 | pubmed:volume | 57 | lld:pubmed |
| pubmed-article:8480681 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8480681 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8480681 | pubmed:pagination | 650-6 | lld:pubmed |
| pubmed-article:8480681 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:8480681 | pubmed:meshHeading | pubmed-meshheading:8480681-... | lld:pubmed |
| pubmed-article:8480681 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8480681 | pubmed:articleTitle | Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patients. | lld:pubmed |
| pubmed-article:8480681 | pubmed:affiliation | Department of Geriatric Medicine and Metabolic Diseases, First Medical School, University of Naples, Italy. | lld:pubmed |
| pubmed-article:8480681 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8480681 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:8480681 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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