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pubmed-article:8419005pubmed:abstractTextNoninvasive assessment of regional myocardial perfusion at rest and after stress is important for the objective evaluation of the effects of coronary artery disease and its response to therapy. Centers that do not have cyclotrons rely on generator-produced radioisotopes for assessment of regional myocardial perfusion with positron emission tomography (PET). The aim of the present study was to develop and implement an approach to quantify regional myocardial perfusion using copper(II) pyruvaldehyde bis-(N4-thiosemicarbazone) (PTSM) labeled with the generator-produced, positron-emitting radionuclide 62Cu (t1/2 = 9.7 minutes).lld:pubmed
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pubmed-article:8419005pubmed:authorpubmed-author:WelchM JMJlld:pubmed
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pubmed-article:8419005pubmed:pagination173-83lld:pubmed
pubmed-article:8419005pubmed:dateRevised2010-3-24lld:pubmed
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pubmed-article:8419005pubmed:articleTitleQuantification of regional myocardial perfusion with generator-produced 62Cu-PTSM and positron emission tomography.lld:pubmed
pubmed-article:8419005pubmed:affiliationCardiovascular Division, Washington University School of Medicine, St. Louis, Mo. 63110.lld:pubmed
pubmed-article:8419005pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8419005pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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