| pubmed-article:8297898 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0021083 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0009404 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0085983 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0019721 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0020964 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C1517945 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8297898 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8297898 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8297898 | pubmed:dateCreated | 1994-3-7 | lld:pubmed |
| pubmed-article:8297898 | pubmed:abstractText | A system devised for tissue typing the human leukocyte antigen-A (HLA-A) locus from genomic DNA by the polymerase chain reaction (PCR) has been used to investigate abnormalities of HLA expression in a panel of 30 cell lines derived from colorectal adenocarcinomas, by comparison of the HLA-A locus genotype with surface expression of HLA. Eleven cell lines gave single HLA-A locus specificity on PCR typing, suggesting that loss of HLA alleles is a common abnormality. In one of these cell lines the loss of an HLA-A locus allele was confirmed by comparison with DNA from a lymphoblastoid B cell line derived from the same patient. In three cell lines, loss of expression of an HLA-A locus determinant was observed in spite of the presence of the relevant allele in genomic DNA. Three cell lines showed absent HLA expression associated with failure to express beta 2-microglobulin. These data indicate that at least three independent mechanisms were involved in the loss of HLA expression on the colorectal tumor cell lines. | lld:pubmed |
| pubmed-article:8297898 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8297898 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8297898 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8297898 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8297898 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8297898 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8297898 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8297898 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8297898 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8297898 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8297898 | pubmed:issn | 1067-5582 | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:KraussBB | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:BodmerW FWF | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:BodmerJ GJG | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:BicknellD CDC | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:HillA BAB | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:BrowningM JMJ | lld:pubmed |
| pubmed-article:8297898 | pubmed:author | pubmed-author:RowanAA | lld:pubmed |
| pubmed-article:8297898 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8297898 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:8297898 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8297898 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8297898 | pubmed:pagination | 163-8 | lld:pubmed |
| pubmed-article:8297898 | pubmed:dateRevised | 2007-5-4 | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
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| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:meshHeading | pubmed-meshheading:8297898-... | lld:pubmed |
| pubmed-article:8297898 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8297898 | pubmed:articleTitle | Loss of human leukocyte antigen expression on colorectal tumor cell lines: implications for anti-tumor immunity and immunotherapy. | lld:pubmed |
| pubmed-article:8297898 | pubmed:affiliation | ICRF, Cancer Immunology Laboratory, John Radcliffe Hospital, Oxford, England. | lld:pubmed |
| pubmed-article:8297898 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8297898 | lld:pubmed |
