| pubmed-article:8268384 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8268384 | lifeskim:mentions | umls-concept:C0599779 | lld:lifeskim |
| pubmed-article:8268384 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:8268384 | lifeskim:mentions | umls-concept:C0250318 | lld:lifeskim |
| pubmed-article:8268384 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:8268384 | pubmed:dateCreated | 1994-2-1 | lld:pubmed |
| pubmed-article:8268384 | pubmed:abstractText | Bone defects were surgically produced in the tibiae of rabbits and medicated with freeze-dried methylpyrrolidinone chitosan. Histological observations 60 d after surgery showed a considerable presence of neoformed bone tissue, as opposed to controls, originating from the pre-existing bone as well as from the periosteum. The cationic nature and the chelating ability of the methylpyrrolidinone chitosan apparently favoured mineralization. Endosteal-periosteal and bone marrow osteoblast-like precursors, stimulated by growth factors entrapped in the coagulum-polysaccharide mixture, gave rise to intramembranous bone formation. The ultrastructural examination evidenced that bone osteoid was followed by mineralization of the tissue. | lld:pubmed |
| pubmed-article:8268384 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8268384 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8268384 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8268384 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8268384 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8268384 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8268384 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8268384 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8268384 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8268384 | pubmed:issn | 0142-9612 | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:MuzzarelliR... | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:BiaginiGG | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:CastaldiniCC | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:PugnaloniAA | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:Mattioli... | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:ZucchiniCC | lld:pubmed |
| pubmed-article:8268384 | pubmed:author | pubmed-author:IlariPP | lld:pubmed |
| pubmed-article:8268384 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8268384 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:8268384 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8268384 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8268384 | pubmed:pagination | 925-9 | lld:pubmed |
| pubmed-article:8268384 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:meshHeading | pubmed-meshheading:8268384-... | lld:pubmed |
| pubmed-article:8268384 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8268384 | pubmed:articleTitle | Osteoconductive properties of methylpyrrolidinone chitosan in an animal model. | lld:pubmed |
| pubmed-article:8268384 | pubmed:affiliation | Institute of Biochemistry, Faculty of Medicine, University of Ancona, Italy. | lld:pubmed |
| pubmed-article:8268384 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8268384 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
