| pubmed-article:8238251 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C1123023 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C0024880 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C1318444 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C0162788 | lld:lifeskim |
| pubmed-article:8238251 | lifeskim:mentions | umls-concept:C1511938 | lld:lifeskim |
| pubmed-article:8238251 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8238251 | pubmed:dateCreated | 1993-12-2 | lld:pubmed |
| pubmed-article:8238251 | pubmed:abstractText | The staining property of skin mast cells changed from Alcian blue+/berberine sulfate- to Alcian blue+/berberine sulfate+ in the skin of normal (+/+) and Wv/Wv mice. In contrast, this change did not occur in the skin of mi/mi mice. Heparin content and histamine content per a mi/mi skin mast cell were estimated to be 34% and 18% those of a +/+ skin mast cell, respectively. The low heparin content of mi/mi skin mast cells seemed to be consistent with the Alcian blue+/berberine sulfate- staining property. Expression of genes encoding mast cell-specific proteolytic enzymes was examined by Northern blotting and in situ hybridization. Messenger RNA of mast cell carboxypeptidase A was expressed most of all by +/+, Wv/Wv, and mi/mi skin mast cells, but mRNA of mouse mast cell protease (MMCP)-6 was expressed by approximately a half of +/+ and Wv/Wv skin mast cells and by only 3% of mi/mi skin mast cells. A significant amount of MMCP-2 mRNA was not expressed in the skin of all +/+, Wv/Wv and mi/mi mice. This shows the presence of at least three phenotypes in skin mast cells of mice: berberine sulfate+/MMCP-6+, berberine sulfate+/MMCP-6-, and berberine sulfate-/MMCP-6-. The in situ hybridization of mRNA of mast cell-specific proteolytic enzymes seemed to be useful to describe abnormalities of mast cell differentiation in the skin of mi/mi mice. | lld:pubmed |
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| pubmed-article:8238251 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8238251 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8238251 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8238251 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8238251 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:8238251 | pubmed:issn | 0002-9440 | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:YoshidaKK | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:TsujimuraTT | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:MorimotoMM | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:YamatodaniAA | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:OguraSS | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:KasugaiTT | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:PálKK | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:Dy?SS | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:IsozakiKK | lld:pubmed |
| pubmed-article:8238251 | pubmed:author | pubmed-author:Jippo-Kanemot... | lld:pubmed |
| pubmed-article:8238251 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8238251 | pubmed:volume | 143 | lld:pubmed |
| pubmed-article:8238251 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8238251 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:8238251 | pubmed:pagination | 1337-47 | lld:pubmed |
| pubmed-article:8238251 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8238251 | pubmed:meshHeading | pubmed-meshheading:8238251-... | lld:pubmed |
| pubmed-article:8238251 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8238251 | pubmed:articleTitle | Deficient differentiation of mast cells in the skin of mi/mi mice. Usefulness of in situ hybridization for evaluation of mast cell phenotype. | lld:pubmed |
| pubmed-article:8238251 | pubmed:affiliation | Department of Pathology, Osaka University Medical School, Suita, Japan. | lld:pubmed |
| pubmed-article:8238251 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8238251 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:17342 | entrezgene:pubmed | pubmed-article:8238251 | lld:entrezgene |
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