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pubmed-article:8203418pubmed:dateCreated1994-7-7lld:pubmed
pubmed-article:8203418pubmed:abstractTextOur purpose was to examine the effects of RU 486 and leuprolide acetate on uterine artery blood flow and uterine volume.lld:pubmed
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pubmed-article:8203418pubmed:authorpubmed-author:SenM KMKlld:pubmed
pubmed-article:8203418pubmed:authorpubmed-author:MoralesA JAJlld:pubmed
pubmed-article:8203418pubmed:authorpubmed-author:MurphyA AAAlld:pubmed
pubmed-article:8203418pubmed:authorpubmed-author:ReinschR CRClld:pubmed
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pubmed-article:8203418pubmed:volume170lld:pubmed
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pubmed-article:8203418pubmed:pagination1623-7; discussion 1627-8lld:pubmed
pubmed-article:8203418pubmed:dateRevised2004-11-17lld:pubmed
pubmed-article:8203418pubmed:otherAbstractPIP: Fourteen women with uterine fibroids and scheduled to undergo either myomectomy or hysterectomy were randomly assigned to take RU-486 and leuprolide acetate over a period of three months to determine their effects upon uterine artery blood flow and uterine volume. Eight patients received 25 mg of RU-486 per day and six patients received 3.75 mg/month of leuprolide acetate over the same period. Uterine artery blood flow change was determined by resistive index by means of vaginal color Doppler ultrasonography, while uterine volume was measured before and during the study with abdominal ultrasonography. Blood flow decreased 40% among those taking RU-486 compared to 21% among those administered leuprolide acetate. Uterine volume decreased significantly for both groups without significant difference in the extent of decrease between groups. Study findings would support the hypothesis that a significant decrease in uterine artery blood flow may provide a mechanism for the decrease in uterine size and the decrease in uterine blood loss at the time of surgery.lld:pubmed
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pubmed-article:8203418pubmed:year1994lld:pubmed
pubmed-article:8203418pubmed:articleTitleThe effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study.lld:pubmed
pubmed-article:8203418pubmed:affiliationDepartment of Obstetrics and Gynecology, Kaiser Permanente, University of California, San Diego 92103.lld:pubmed
pubmed-article:8203418pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8203418pubmed:publicationTypeClinical Triallld:pubmed
pubmed-article:8203418pubmed:publicationTypeRandomized Controlled Triallld:pubmed
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