| pubmed-article:8133114 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8133114 | lifeskim:mentions | umls-concept:C0005767 | lld:lifeskim |
| pubmed-article:8133114 | lifeskim:mentions | umls-concept:C0003374 | lld:lifeskim |
| pubmed-article:8133114 | lifeskim:mentions | umls-concept:C0024537 | lld:lifeskim |
| pubmed-article:8133114 | lifeskim:mentions | umls-concept:C0033126 | lld:lifeskim |
| pubmed-article:8133114 | lifeskim:mentions | umls-concept:C1306673 | lld:lifeskim |
| pubmed-article:8133114 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8133114 | pubmed:dateCreated | 1994-4-18 | lld:pubmed |
| pubmed-article:8133114 | pubmed:abstractText | The blood stage antimalarial efficacy of primaquine (0.25 mg of base/kg of body weight/day over 14 days) and chloroquine (25 mg of base/kg over 3 days) were compared in 85 adult Thai men with acute Plasmodium vivax malaria. Most (75%) had at least one malaria episode previously. Parasite clearance times after primaquine alone (n = 30) were slower than after chloroquine (n = 30) or combined chloroquine-primaquine (n = 25), but all patients had a satisfactory initial therapeutic response. P. vivax malaria recurred in 10 (17%) of 60 patients followed for > or = 2 months and Plasmodium falciparum malaria developed in another 5 (8%) without reexposure to infection. Recurrences occurred < or = 5 weeks after primaquine treatment (n = 4), suggesting recrudescence, whereas recurrences after chloroquine treatment (n = 6) occurred > or = 5 weeks later, suggesting relapse. Vivax malaria responds well initially to either primaquine or chloroquine. The blood stage antimalarial activity of primaquine may mask chloroquine resistance in combined regimens. | lld:pubmed |
| pubmed-article:8133114 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8133114 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8133114 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8133114 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:8133114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8133114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8133114 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8133114 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8133114 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:8133114 | pubmed:author | pubmed-author:ClemensRR | lld:pubmed |
| pubmed-article:8133114 | pubmed:author | pubmed-author:VanijanontaSS | lld:pubmed |
| pubmed-article:8133114 | pubmed:author | pubmed-author:WhiteN JNJ | lld:pubmed |
| pubmed-article:8133114 | pubmed:author | pubmed-author:Pukrittayakam... | lld:pubmed |
| pubmed-article:8133114 | pubmed:author | pubmed-author:ChantraAA | lld:pubmed |
| pubmed-article:8133114 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8133114 | pubmed:volume | 169 | lld:pubmed |
| pubmed-article:8133114 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8133114 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8133114 | pubmed:pagination | 932-5 | lld:pubmed |
| pubmed-article:8133114 | pubmed:dateRevised | 2010-8-25 | lld:pubmed |
| pubmed-article:8133114 | pubmed:meshHeading | pubmed-meshheading:8133114-... | lld:pubmed |
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| pubmed-article:8133114 | pubmed:meshHeading | pubmed-meshheading:8133114-... | lld:pubmed |
| pubmed-article:8133114 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8133114 | pubmed:articleTitle | Blood stage antimalarial efficacy of primaquine in Plasmodium vivax malaria. | lld:pubmed |
| pubmed-article:8133114 | pubmed:affiliation | Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. | lld:pubmed |
| pubmed-article:8133114 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8133114 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:8133114 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:8133114 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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